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Deposition, critical loads, and exceedances for 1800-2025
This data includes gridded estimates of: (1) decadally averaged total N and S deposition for the conterminous US from 1800-2025, (2) critical loads from the National Critical... -
Toward an AOP Network-based tiered testing strategy for the assessment of thy...
No novel data were reported in association with this product. This dataset is not publicly accessible because: The associated publication is a review/forum-type article. No... -
Representing the Process of Inflammation as Key Events in Adverse Outcome Pat...
A set of three proposed "hub" key events were used to link together a series of example adverse outcome pathway (AOP) descriptions that were previously not linked in an AOP... -
In vivo and In vitro neurochemical-based assessments of wastewater effluents ...
All primary data reported in this paper were generated by non-federal collaborators from the University of Michigan and McGill University. US EPA-ORD personnel collected and... -
Adverse Outcome Pathway Network-Based Assessment of the Interactive Effects o...
Adverse outcome pathway (AOP) networks potentially provide a basis for predictive approaches to assess the toxicity of chemical mixtures. This study evaluated the utility of a... -
Data from "A method for CRISPR/Cas9 mutation of genes in fathead minnow (Pime...
The dataset includes survival of control, control injected, and CRISPR/Cas9 injected embryos as well as percent efficiency of insertion/deletion mutation formation for the three... -
Adverse Outcome Pathway Networks I: Development and Applications
In September, 2015, a water sample was collected downstream of a major metropolitan waste water treatment plant that discharges to the South Platte River, Colorado, USA. The... -
Adverse Outcome Pathway Networks II: Network Analytics
The data set provides a set of txt files and cytoscape files that were used to construct the example AOP networks included in the paper. Additionally, a supplementary table file... -
An Integrated Approach for Identifying Priority Contaminant in the Great Lake...
Prioritization of chemicals was performed on two Areas of Concerns in the Great Lakes An integrated risk surveillance and monitoring approach was applied Bio-effect prediction... -
Prior knowledge-based approach for associating contaminants with biological e...
Concentrations of 127 organic chemicals measured in water samples collected from five locations in proximity to two municipal wastewater treatment plants in the St. Croix River... -
Effects of the antimicrobial contaminant triclocarban, and co-exposure with t...
Triclocarban (TCC) is a widely used antimicrobial agent that is routinely detected in surface waters. The present study was designed to examine TCC’s efficacy and mode of action... -
Derivation and Evaluation of Putative Adverse Outcome Pathways for Effects of...
Fathead minnows (Pimephales promelas) were exposed to 100 ug/L indomethacin, 200 ug/L ibuprofen, or 20 ug/L celecoxib for 96 h. Effects on cycloxygenase enzyme activity in...