The data resource consists of half hourly time series of heat (latent and sensible) and trace gas (carbon dioxide and methane) fluxes obtained by eddy-covariance, gas concentrations and ancillary meteorological data (e.g. air temperature, relative humidity, pressure, photosynthetically active radiation, total incoming radiation, wind speed and direction). The data were collected at Guma Lagoon (18°57'53.01'S; 22°22'16.20'E), in the perennially flooded area of the Okavango Delta, Botswana, for the purpose of quantifying greenhouse gas fluxes over a Cyperus papyrus stand. The measurement period was 01/01/2018 to 31/12/2020. The instrumentation was installed the UK Centre for Ecology and Hydrology; monthly maintenance and data collection visits were effected by the Okavango Research Institute, University of Botswana. The research was funded through NERC grant reference NE/N015746/2 - The Global Methane Budget.